Ответ:

1. Although that shop is popular, it is a ling way from the city centere

2. Even if we have got a car, we prefer to take the bus into town

3. Despite being the right size they didn't feel comfortable

Despite the fact that jeans feel uncomfortable they were the right size

4. In spite of there being a big queue I decided to wait

In spite of the fact that there were a bug queue I decided to wait